Her other films include Along Came Polly (2004) and He's Just Not That Into You (2009).

Crazy antics involving a poisonous spider and inter-familial kissing lessons ensue. And Jason has the right kind of biting humor that the role required. He can be both charming and just a little bit of a jerk. The niceness is all there, but there is also an understanding that it has to be good."Aniston jokes that the selling point of their film was her aggressively homely mom attire. I love the full circle of how she's closed off and a little broken down and beaten up. I was in the kind of shape I don't enjoy being in because it feels a little too fit. "And the workouts I had to do were so torturous and you just dread it. We're not trying to anger people."Her tactic: Be as choosy as possible about what you do, and then go back and live your life."As we've gotten older, you realize that life is so short and the passage of time is so important and precious, so if you're going to be three months anywhere, you better have something enjoyable and wonderful you're doing.

It's the third time Aniston and Sudeikis are paired up on film, after 2010's The Bounty Hunter and 2011's Horrible Bosses. From my perspective, they were friends coming into the movie. It's good when men are in touch with their emotional selves and are not inhibited and intimidated to show that."Sudeikis, 37, draws attention to her unwavering politeness and professionalism."Jen's lovely to everybody," he says. There's an appreciation of the team and talent that goes into all this stuff. At the heart of everybody in the movie, they're desiring to be loved and have a family. It's nice to be thoughtful in the process of deciding things. Then I said yes and you supported me."In fact, Thurber confirms, Aniston "doesn't get enough credit for how funny she is in person. I'm getting to the point of, 'Where is it shooting?

She then co-starred in Ferris Bueller, a television adaptation of the movie Ferris Bueller's Day Off (1986), and like Molloy also quickly canceled.

Aniston then appeared in two more failed television comedy series, The Edge and Muddling Through.

I try to incorporate them into positivity and chalk it up to great experiences," Aniston says. But let's not talk about that."Talk turns to being nice, and Aniston refers to an actor, whom she won't name, who revels in being unpleasant and cantankerous to those around him.

The latest speculation, after a fuller figure she showcased at the premiere of We're the Millers Aug. That she's (again) pregnant, which her longtime publicist, Stephen Huvane, says is not true. "Eventually if you start doing that, you won't be asked to come and play in the movie," Aniston says. The actress has no financial incentive to work, given the paychecks earned by her and her Friends castmates during the final season of their show.I was a kid and I was riding this tricycle around a swimming pool and I drove my tricycle into the swimming pool and I didn't let go and my brother tried to (help).So, I can't go underwater and no one will believe me.I saw the part that was a little closed up and beaten down by disappointments."Aniston's Rose teams up with Jason Sudeikis' small-time pot dealer Dave to haul an RV full of marijuana across the border from Mexico. I like that Dave starts out selfish and he ends up being a little selfless."Director Rawson Marshall Thurber had seen Aniston's lascivious dentist in Bosses and was smitten."She stole the show there and was funny and fearless. You can't embarrass her."She can hang with the boys. She's not a wallflower."Without question, Aniston and Sudeikis, who's quick on his feet, easily go toe to toe, zinging from Sudeikis' departure from NBC's Saturday Night Live — "Selfishly, I'm sad," laments Aniston, to which he promises to get her a boxed set — to the physical training she took on for her pivotal pole dancing scene, something of an homage to Flashdance. But ask Aniston, and she'll tell you the work isn't the issue. The side of it, the media side of it, very much overshadowing the stuff we get to do.To help fool the authorities, they're joined by a fake son and daughter. She could hold the screen with Jason and she has a natural mothering nature to her. We developed her and gave her a bit more of a story. Even for someone as physically honed as Aniston, the choreography was brutal."It wasn't easy, because I'd just had knee surgery a month and a half before. And then also just getting trained physically — I was really in shape then. You stand up and jump up and do push ups."So even Aniston, she of the toned yoga bod, has issues? My body and genetics — my mother gave me a big (butt). Sometimes it likes to takes trips to the right and we have to get it to come back. It's everything else."I get frustrated all the time. We're all just trying to do our best in order to entertain people.In 2015, she spoke about a childhood incident that led to her lifelong fear of water.